Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy

Recruiting now · Not applicable

Conditions studied: Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis, Vestibular Neuronitis, Labyrinthitis, Herpes Zoster Oticus

In brief

This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of adjunct take-home head-mounted display (HMD) virtual reality (VR) therapy in improving patient symptomatology. Fifty patients meeting inclusion criteria will be recruited from the principal investigator's neurotology clinic. Baseline symptomatology questionnaires will be completed, followed by random allocation to virtual reality and control groups. Vestibular rehabilitation and virtual reality protocols will be adhered to for 4 to 8 weeks, followed by symptomatology questionnaires. Data analysis will be conducted to answer the study's objectives.

Key facts

Study ID

NCT05424302

Run by

University of British Columbia

People needed

50

Starts

2024-06-01

Expected to finish

2026-09-01

Last updated by the study team

2024-08-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participants diagnosed with chronic (≥3 months) unilateral or bilateral peripheral vestibular disorders such as vestibular neuritis, labyrinthitis, Ramsay Hunt syndrome, ischemic lesion and trauma.
• Diagnosis made using caloric testing (≥25% reduced vestibular response) and either ocular vestibular evoked myogenic potential (oVEMP) or cervical vestibular evoked myogenic potential (cVEMP) testing.
• Participants prescribed vestibular rehabilitation
• Participants ≥18 years of age
• Access to an android or iOS smart phone

You may not qualify if…

• Pregnant participants
• Participant diagnosed with a central vestibular disorder

Where it is running

• University of British Columbia — Vancouver, British Columbia, Canada (enrolling)

Full record on ClinicalTrials.gov

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