INSPIRE Trial for Skin and Soft Tissue Infections
Completed · Not applicable
Conditions studied: Skin and Soft Tissue (SST) Infection
In brief
The INSPIRE Skin and Soft Tissue Infection trial is a cluster-randomized controlled trial of HCA Healthcare hospitals comparing routine empiric antibiotic stewardship practices with real-time, precision medicine computerized physician order entry (CPOE) smart prompts providing the probability that a non-critically ill adult admitted with skin and soft tissue infection is infected with a resistant pathogen. Note: enrolled "subjects" represent 102 individual HCA Healthcare hospitals that have been randomized into 92 clusters. Hospitals were grouped into the same randomization cluster if they shared campuses or antibiotic stewardship staff.
Key facts
- Study ID
- NCT05423756
- Run by
- Harvard Pilgrim Health Care
- People needed
- 118562
- Starts
- 2023-01-01
- Expected to finish
- 2024-05-09
- Last updated by the study team
- 2025-08-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Regional Medical Center of San Jose — San Jose, California, United States
- Good Samaritan Hospital — San Jose, California, United States
- Los Robles Hospital & Medical Center — Thousand Oaks, California, United States
- West Hills Hospital & Medical Center — West Hills, California, United States
- The Medical Center of Aurora — Aurora, Colorado, United States
- Swedish Medical Center — Englewood, Colorado, United States
- Sky Ridge Medical Center — Lone Tree, Colorado, United States
- North Suburban Medical Center — Thornton, Colorado, United States
- Blake Medical Center — Bradenton, Florida, United States
- Brandon Regional Hospital — Brandon, Florida, United States
- Oak Hill Hospital — Brooksville, Florida, United States
- Englewood Community Hospital — Englewood, Florida, United States
- Fort Walton Beach Medical Center — Fort Walton Beach, Florida, United States
- Lawnwood Regional Medical Center — Ft. Pierce, Florida, United States
- Regional Medical Center Bayonet Point — Hudson, Florida, United States
- Memorial Hospital Jacksonville — Jacksonville, Florida, United States
- Lake City Medical Center — Lake City, Florida, United States
- Largo Medical Center — Largo, Florida, United States
- Northwest Medical Center — Margate, Florida, United States
- Mercy Hospital — Miami, Florida, United States
- Kendall Regional Medical Center — Miami, Florida, United States
- Orange Park Medical Center — Orange Park, Florida, United States
- Oviedo Medical Center — Oviedo, Florida, United States
- Gulf Coast Regional Medical Center — Panama City, Florida, United States
- Riverside Community hospital — Riverside, California, United States
Full record on ClinicalTrials.gov
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