Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures
Recruiting now · Not applicable
Conditions studied: Pain, Postoperative, Rib Fracture Multiple
In brief
To determine if patients with intraoperative cryoablation have better analgesia results compared to the control group of Surgical Stabilization of Rib Fractures (SSRF) without cryoablation
Key facts
- Study ID
- NCT05415384
- Run by
- Wake Forest University Health Sciences
- People needed
- 80
- Starts
- 2022-08-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-06-29
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- The patient is admitted to the trauma service.
- The patient has multiple displaced rib fractures (≥2 ribs), offered fixation, and consents to SSRF
- The patient is not being treated for chronic pain
- The patient is >18 years of age.
- Surgery anticipated <120 hours from injury
You may not qualify if…
- Age < 18 years or ≥ 80 years
- Flail chest: either radiographic or clinical. Radiographic flail chest is defined on CT chest as ≥ 2 ribs each fractured in ≥ 2 places. Clinical flail is defined as visualization of a segment of chest wall with paradoxical motion on physical exam.
- Moderate or severe traumatic brain injury (Intra-cranial hemorrhage visualized on CT head with GCS at the time of consideration for enrollment < 12)
- Prior or expected emergency exploratory laparotomy during this admission
- Prior or expected emergency thoracotomy during this admission
- Prior or expected emergency craniotomy during this admission
- Spinal cord injury
- Pelvic fracture that has required, or is expected to require, operative intervention during this admission
- The patient was unable to accomplish activities of daily living independently prior to injury (e.g., dressing, bathing, preparing meals)
- The patient is incarcerated
- The patient is known to be pregnant
- Unable to perform Video Assisted Thoracoscopy (VATS) at time of SSRF due to lung isolation or previous pathology
Where it is running
- Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.