The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
Recruiting now · Not applicable
Conditions studied: Peri-Implantitis
In brief
The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone grafting/implantoplasty in patients who undergo surgical therapy of peri-implantitis with respect to clinical resolution of the infection.
Key facts
- Study ID
- NCT05415111
- Run by
- Nadja Naenni
- People needed
- 120
- Starts
- 2022-10-31
- Expected to finish
- 2029-12-01
- Last updated by the study team
- 2024-05-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age > 18 years old (UZH, FRA) or > 21 years old (SIN), male and female.
- Diagnosed with periimplantitis of at least 1 implant in function for at least 1 year Diagnostic criteria
- Presence of bleeding and/or suppuration on gentle probing.
- Probing depths of ≥6 mm.
- Bone levels ≥3 mm apical of the most coronal portion of the intraosseous part of the implant.
- Periodontal health (including previously treated periodontitis patients with reduced but healthy periodontium)
- Good oral hygiene (full mouth plaque score <25%)
- Adequate control of inflammation (full mouth BOP <25%)
- Signed informed consent form
You may not qualify if…
- Pregnant or lactating female patient at inclusion
- Allergy or objection to porcine and bovine implantable biomaterials
- Allergy to Penicillin or NSAIDs
- Known or suspected non-compliance, drug or alcohol abuse
- Inability to follow the procedures of the study, e.g. due to language/ comprehension problems, psychological disorders, dementia, etc. of the participant
- Smoking > 15 cigarettes a day
- Active periodontal disease
Where it is running
- Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich — Zurich, Switzerland (enrolling)
- Department of Oral Surgery and Implantology, Centre for Dentistry and Oral Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt — Frankfurt, Germany
- National Dental Centre Singapore — Singapore, Singapore
Full record on ClinicalTrials.gov
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