Positive Emotions Following Acute Cardiac Events

Recruiting now · Not applicable

Conditions studied: Acute Coronary Syndrome, Physical Inactivity

In brief

The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 12 weeks), compared to post-acute coronary syndrome (ACS) treatment as usual, in a randomized trial of 280 post-ACS patients with low baseline physical activity.

Key facts

Study ID

NCT05412862

Run by

Massachusetts General Hospital

People needed

280

Starts

2022-09-12

Expected to finish

2028-03-31

Last updated by the study team

2026-04-20

Who can join

Age: 18 and older, up to 95. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ACS (myocardial infarction or unstable angina)
• Suboptimal physical activity (score of < 6 on the Medical Outcomes study Specific Adherence Scale item related to physical activity)

You may not qualify if…

• Cognitive deficits (assessed via a 6-item cognitive screening tool)
• Medical conditions likely to lead to death within 6 months.
• Moderate-severe depression (Patient Health Questionnaire-9 [PHQ-9] score ≥15)
• Inability to participate in physical activity due to another medical condition (e.g., arthritis)
• Inability to read, write, or speak in English
• Inability to receive text-messages
• Current participation in another intervention or program that has been designed to promote well-being or physical activity

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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