NGS in Gallbladder Cancer and Response to Treatment

Recruiting now

Conditions studied: Gallbladder Cancer

In brief

Evidence suggests distinct models of molecular and pathologic progression, and a growing body of genetics data points to a heterogeneous collection of underlying mutations in key oncogenes and tumor suppressor genes. Although tumor genetics have been used to tailor individual treatment regimens and guide clinical decision making in other cancers, these principles have not been applied in gallbladder malignancy. Recent clinical trials with targeted therapies seem promising, although the relationships between subsets of patients with positive responses to therapy and tumor genetics remain unexplored.

Key facts

Study ID

NCT05404347

Run by

Banaras Hindu University

People needed

100

Starts

2018-01-01

Expected to finish

2026-12-31

Last updated by the study team

2024-08-13

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Treatment naïve patients with histologically proven carcinoma of the gallbladder.

You may not qualify if…

• No histological evidence of malignancy
• Pregnant and lactating women

Where it is running

• Banaras Hindu University — Varanasi, Uttar Pradesh, India (enrolling)

Full record on ClinicalTrials.gov

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