SDF Application in Oral Cancer Patients to Prevent Dental Caries

Completed · Early Phase 1 · Has a placebo group

Conditions studied: Dental Caries

In brief

The Texas A \& M College of Dentistry, with partner Texas Oncology-Baylor Charles A. Sammons Cancer-Center Radiation-Oncology, proposes to conduct a preliminary clinical study (NIH Stage 0) to pilot test a randomized clinical trial of the efficacy of professionally applied 38% silver diamine fluoride to prevent tooth decay in 60 patients who are being treated with radiation for life threatening head and neck cancer.

Key facts

Study ID

NCT05403125

Run by

Texas A & M University Baylor College Of Dentistry

People needed

56

Starts

2022-05-20

Expected to finish

2025-03-18

Last updated by the study team

2025-09-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of Head and Neck cancer

You may not qualify if…

• Prognosis less than 1 year
• Radiation field of treatment does not involve jaws

Where it is running

• Baylor College of Dentistry — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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