A Study to Evaluate the Efficacy and Safety of Rencofilstat in Subjects With NASH and Advanced Liver Fibrosis
Status unconfirmed · Phase 2 · Has a placebo group
Conditions studied: Nonalcoholic Steatohepatitis (NASH), Fibrosis, Liver, NAFLD
In brief
This is a randomized, double-blind, placebo-controlled, parallel-dosing, multi-center study to evaluate the efficacy and safety of Rencofilstat as evidenced by histopathological improvements in fibrosis in adult NASH subjects with F2 or F3 fibrosis (NASH CRN system). Antifibrotic biomarker activity will be evaluated on an exploratory basis.
Key facts
- Study ID
- NCT05402371
- Run by
- Hepion Pharmaceuticals, Inc.
- People needed
- 120
- Starts
- 2022-10-15
- Expected to finish
- 2025-09-01
- Last updated by the study team
- 2024-05-03
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Medical Affiliated Research Center — Huntsville, Alabama, United States
- Arizona Liver Health-Chandler — Chandler, Arizona, United States
- Arizona Liver Health — Peoria, Arizona, United States
- Adobe Clinical Research, LLC — Tucson, Arizona, United States
- Arizona Liver Health-Tuscon — Tucson, Arizona, United States
- Preferred Research Partners, Inc. — Little Rock, Arkansas, United States
- Arkansas Gastroenterology — North Little Rock, Arkansas, United States
- National Research Institute — Huntington Park, California, United States
- National Research Institute — Los Angeles, California, United States
- National Research Institute — Panorama City, California, United States
- National Research Institute — Santa Ana, California, United States
- Synergy Healthcare, LLC — Bradenton, Florida, United States
- Tampa Bay Medical Research, Inc. — Clearwater, Florida, United States
- Top Medical Research, Inc. — Cutler Bay, Florida, United States
- Integrity Clinical Research, LLC — Doral, Florida, United States
- Evolution Clinical Trials, Inc. — Hialeah Gardens, Florida, United States
- Borland Groover Clinical Research — Jacksonville, Florida, United States
- Ocala GI Research — Lady Lake, Florida, United States
- Accel Research Sites-Lakeland CRU — Lakeland, Florida, United States
- Future Care Solutions, LLC — Miami, Florida, United States
- Entrust Clinical Research — Miami, Florida, United States
- United Reseach Group — Miami, Florida, United States
- Omega Research Consultants, LLC — Orlando, Florida, United States
- Progressive Medical Research — Port Orange, Florida, United States
- Covenant Research and Clinics — Sarasota, Florida, United States
Full record on ClinicalTrials.gov
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