Characterization of Endocannabinoid and Endogenous Opioid Levels in Adolescents With Cannabis Use Disorder

Running, not enrolling · Not applicable

Conditions studied: Cannabis Use

In brief

This project seeks to learn more about the effects of cannabis use on the endocannabinoid system and endogenous opioid systems in adolescents to address a fundamental gap in knowledge and identify biomarkers that may help distinguish youth who relapse from youth who remain sober.

Key facts

Study ID

NCT05396638

Run by

University of Colorado, Denver

People needed

30

Starts

2022-10-13

Expected to finish

2026-12-01

Last updated by the study team

2026-05-01

Who can join

Age: 14 and older, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 14 to 25 years of age.
• Use cannabis at least twice a week for the past month.

You may not qualify if…

• Refusal of valid written consent,
• Current psychosis,
• Obvious intoxication,
• Current risk of suicide,
• Violence sufficiently great to interfere with evaluation or to endanger evaluators,
• Obvious intellectual deficiency as noted during the informed consent process, or inability of patient or family to comply with the study protocol.
• Use of other illicit drugs in the past 90 days by self-report or detected by urine drug test.
• Use of opioid medications for medical or recreational purposes currently or within the past 90 days.
• Does not have access to an Internet connected devise or cannot use Zoom.

Where it is running

• University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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