The Effect of Sleep Loss on Emotion Regulation

Recruiting now · Not applicable

Conditions studied: Sleep, Insomnia, Sleep Deprivation

In brief

The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced sleep or a diagnosis of Insomnia Disorder affect the processing and regulation of emotional information compared to typical, undisturbed sleep? (ii) What overlapping and distinct neural mechanisms are engaged and associated with behavioral effects when attempting to process and regulate emotions in a sleep restricted state or with a clinical diagnosis of Insomnia Disorder? This study will investigate sleep's role in emotion processing and regulation. The findings will help further understanding of the role of sleep in healthy emotional functioning.

Key facts

Study ID: NCT05393830
Run by: Beth Israel Deaconess Medical Center
People needed: 90
Starts: 2023-05-11
Expected to finish: 2027-07-31
Last updated by the study team: 2026-04-14

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

willing and able to follow the protocol
willing and able to meet inclusion criteria for fMRI scanning
willing to refrain from alcohol and recreational drugs for the duration of the protocol
normal or corrected to normal vision is required

You may not qualify if…

left-handedness or ambidexterity
the use of any drugs that could affect either sleep or cognitive functioning (e.g., prescription sleeping pills or antidepressants)

Where it is running

Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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