Electroclinical Correlation of Anxiety

Recruiting now · Not applicable

Conditions studied: Anxiety Disorder, Generalized Anxiety Disorder, Drug Resistant Epilepsy

In brief

Anxiety disorders have the highest prevalence among mental disorders and cause considerable individual and financial costs. Current treatments do not relieve mental suffering of many patients. Understanding neurobiological mechanisms involved in pathological anxiety is a major scientific challenge.

Key facts

Study ID

NCT05393518

Run by

University Hospital, Bordeaux

People needed

30

Starts

2022-10-11

Expected to finish

2026-10-11

Last updated by the study team

2025-07-25

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Man or woman
• Aged 18 to 65;
• With drug-resistant epilepsy
• Benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG
• Meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("pathological" population) or not meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("control" population)
• WAIS IV full scale IQ > 75 or IAG > 81
• Affiliate or beneficiary of a social security scheme
• Giving free, informed consent in writing and signed by the participant and the investigator

You may not qualify if…

• Being unable to give personal consent
• Be subject to a measure of legal protection (curatorship, guardianship) or placed under judicial protection;
• Suffer from a chronic delusional disorder (eg: schizophrenia);
• Have a moderate or high risk of suicide assessed using the corresponding section of the structured psychiatric interview called "Mini International Neuropsychiatric Interview" (M.I.N.I. 7.0) or a score > 2 on item 10 of the MADRS, assessing suicidal risk;
• Being pregnant or breastfeeding
• Have severe and / or decompensated somatic illness other than drug-resistant epilepsy

Where it is running

• CHU de Bordeaux — Bordeaux, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.