Cannabis' Impact on Alcohol Consumption

Recruiting now · Phase 2 · Has a placebo group

Conditions studied: Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder

In brief

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.

Key facts

Study ID

NCT05389930

Run by

Brown University

People needed

350

Starts

2023-03-16

Expected to finish

2027-03-31

Last updated by the study team

2024-08-06

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 21 to 50
• English-speaking
• cannabis smoking in past two months
• heavy drinking in past two months
• in good physical health and weighing < 250 lbs
• zero breath alcohol at each visit

You may not qualify if…

• positive pregnancy test
• nursing
• positive urine toxicology screen for drugs other than cannabis
• interest to quit or receive treatment for cannabis or alcohol use

Where it is running

• Brown University — Providence, Rhode Island, United States (enrolling)

Full record on ClinicalTrials.gov

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