A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH

Running, not enrolling · Phase 3

Conditions studied: Paroxysmal Nocturnal Hemoglobinuria

In brief

This is a single-arm long-term extension study that will enroll participants with PNH who have completed participation in Alexion-sponsored clinical studies with danicopan as an add on therapy to a C5i.

Key facts

Study ID
NCT05389449
Run by
Alexion Pharmaceuticals, Inc.
People needed
80
Starts
2022-10-28
Expected to finish
2026-08-24
Last updated by the study team
2026-06-18

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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