Valuation in Depressed Mood, Anhedonia, and Anxiety

Recruiting now · Not applicable

Conditions studied: Neurobehavioral Components of Reward and Loss Valuation

In brief

This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and/or anxiety.

Key facts

Study ID

NCT05384158

Run by

Virginia Polytechnic Institute and State University

People needed

252

Starts

2021-08-01

Expected to finish

2026-07-01

Last updated by the study team

2025-09-09

Who can join

Age: 25 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• mood, anxiety, or anhedonia symptoms that affect functioning; fluent in English; able to see computer display; able to perform simple computer games.

You may not qualify if…

• history of seizure disorder, stroke, or head injury with more than 10 minutes of unconsciousness; hormone disorder; electroconvulsive therapy within 5 years; history of chemotherapy for cancer; current pregnancy; contraindications to MRI

Where it is running

• Fralin Biomedical Research Institute at Virginia Tech Carilion — Roanoke, Virginia, United States (enrolling)

Full record on ClinicalTrials.gov

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