A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors
Stopped early · Phase 1
Conditions studied: Solid Tumor, Adult
In brief
This study aims to understand how safe and well-tolerated a drug called BGB-24714 is when used alone, or in combination with chemotherapy or radiation therapy, for people with advanced or spreading solid tumors. The main objective is to identify the highest tolerable dose or the highest administered dose of BGB-24714. Additionally, the study aims to identify the most suitable doses for further investigation in larger groups of participants.
Key facts
- Study ID
- NCT05381909
- Run by
- BeiGene
- People needed
- 157
- Starts
- 2022-07-06
- Expected to finish
- 2025-07-25
- Last updated by the study team
- 2026-02-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Banner Md Anderson Cancer Center — Gilbert, Arizona, United States
- Florida Cancer Specialist (Scri) Sarasota — Sarasota, Florida, United States
- Scri Florida Cancer Specialists North — St. Petersburg, Florida, United States
- Scri Florida Cancer Specialist East — West Palm Beach, Florida, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
- Hackensack University Medical Center — Hackensack, New Jersey, United States
- Upmc Hillman Cancer Center(Univ of Pittsburgh) — Pittsburgh, Pennsylvania, United States
- Sanford Cancer Center — Sioux Falls, South Dakota, United States
- Avera Cancer Institute — Sioux Falls, South Dakota, United States
- Tennessee Oncology, Pllc Nashville — Nashville, Tennessee, United States
- Mary Crowley Cancer Research — Dallas, Texas, United States
- University of Texas Southwestern Medical Center — Dallas, Texas, United States
- The University of Texas Md Anderson Cancer Center (Department Gi Medical Oncology) — Houston, Texas, United States
- Intermountain Healthcare — Salt Lake City, Utah, United States
- Next Virginia — Fairfax, Virginia, United States
- University of Washington — Seattle, Washington, United States
- Northern Beaches Hospital — Frenchs Forest, New South Wales, Australia
- Icon Cancer Centre South Brisbane — South Brisbane, Queensland, Australia
- Princess Alexandra Hospital — Woolloongabba, Queensland, Australia
- Austin Health — Heidelberg, Victoria, Australia
- Peter Maccallum Cancer Centre — Melbourne, Victoria, Australia
- Sunshine Hospital — St Albans, Victoria, Australia
- Chongqing Cancer Hospital — Chongqing, Chongqing Municipality, China
- Henan Cancer Hospital — Zhengzhou, Henan, China
Full record on ClinicalTrials.gov
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