The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Recruiting now · Not applicable

Conditions studied: Ventilatory Depression, Postoperative Respiratory Failure

In brief

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Key facts

Study ID

NCT05379673

Run by

Stanford University

People needed

60

Starts

2022-10-04

Expected to finish

2026-12-01

Last updated by the study team

2025-05-16

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• American Society of Anesthesiologists (ASA) physical status I-III
• Body mass index (BMI) less than 40 kg/m2
• Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.

You may not qualify if…

• Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
• Chronic pain condition that is being treated with opioids
• Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

Where it is running

• Stanford University School of Medicine — Stanford, California, United States (enrolling)

Full record on ClinicalTrials.gov

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