Met Non Small Cell Cancer Registry (MOMENT)

Recruiting now

Conditions studied: Cancer

In brief

The purpose of this multi-national disease registry is to collect prospectively (with longitudinal follow-up) high-quality, standardized, and contemporaneous data to capture changes in the non-small cell lung cancer (NSCLC) treatment landscape and outcomes over time. The registry will capture data on participants; demographic, clinical characteristics (including biomarker data), treatment patterns, and effectiveness and safety outcomes for advanced NSCLC with mesenchymal-epithelial transition exon 14(METex14) participants treated with systemic therapy.

Key facts

Study ID

NCT05376891

Run by

EMD Serono Research & Development Institute, Inc.

People needed

700

Starts

2022-10-04

Expected to finish

2028-04-28

Last updated by the study team

2026-07-13

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants who signed ICF
• Participants with advanced stage (stages IIIB-IV) NSCLC (all histologies) and Confirmed METex14 skipping alterations (by valid assay)
• Participants who are starting or are already being treated with systemic therapy

You may not qualify if…

• Participants who are enrolled in a clinical trial

Where it is running

• The Ohio State University Wexner Medical Center — Columbus, Ohio, United States (enrolling)
• Holy Cross Health — Fort Lauderdale, Florida, United States (enrolling)
• Klinikum Klagenfurt Am Woerthersee — Klagenfurt, Austria (enrolling)
• Klinik Floridsdorf — Vienna, Austria (enrolling)
• AZ Delta — Roeselare, Belgium (enrolling)
• AZ Nikolaas — Sint-Niklaas, Belgium (enrolling)
• Ottawa Hospital General Campus — Ottawa, Canada (enrolling)
• Princess Margaret Cancer Centre — Toronto, Canada (enrolling)
• British Columbia Cancer Agency (6864) — Vancouver, Canada (enrolling)
• FN Olomouc — Olomouc, Czechia (enrolling)
• University Hospital Na Bulovce — Prague, Czechia (enrolling)
• Centre Hospitalier de Cholet — Cholet, France (enrolling)
• CHRU Lille — Lille, France (enrolling)
• Hôpital du Scorff — Lorient, France (enrolling)
• Centre Leon Berard — Lyon, France (enrolling)
• Hospital Tenon & University Paris 6 — Paris, France (enrolling)
• Institut Curie - Centre de Lutte Contre le Cancer (CLCC) — Paris, France (enrolling)
• CHU de Pontchaillou — Rennes, France (enrolling)
• CHU de Toulouse Hopital Larrey — Toulouse, France (enrolling)
• Klinikum Chemnitz GmbH — Chemnitz, Germany (enrolling)
• KKH Grosshansdorf GmbH — Großhansdorf, Germany (enrolling)
• Thoraxklinik-Heidelberg gGmbH — Heidelberg, Germany (enrolling)
• Klinik Löwenstein GmbH — Löwenstein, Germany (enrolling)
• Haemek Medical Center — Afula, Israel (enrolling)
• Bnei-Zion Medical Center — Haifa, Israel (enrolling)

Full record on ClinicalTrials.gov

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