Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA
Recruiting now · Not applicable
Conditions studied: Hepatocellular Carcinoma
In brief
The goal of the REMNANT study is to confirm the clinical value of detecting a new biomarker, ctDNA (circulating tumor DNA), in the follow-up of patients with operated liver cancer. In order to meet this objective, this biomarker will be measured in your blood before and after surgery, at three and six months.
Key facts
- Study ID
- NCT05375370
- Run by
- University Hospital, Rouen
- People needed
- 150
- Starts
- 2022-08-04
- Expected to finish
- 2029-02-01
- Last updated by the study team
- 2026-02-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- HCC diagnosed on consensus radiological criteria in cirrhotic patients (EASL-EORTC 2012): helical CT or MRI with triple arterial, portal and late acquisition. The diagnosis is based on the presence of hypervascularization at the early arterial time (wash-in) with wash-out (hypodensity or hypointensity compared to non-tumor liver parenchyma) at the portal phase or late phase compared to non-tumor parenchyma.
- HCC diagnosed histologically in the absence of a diagnosis on imaging (see IC n°2 above)
- Patient operated on for liver resection or radiofrequency destruction
- Treatment decision validated by the digestive oncology PCR
- Patient having read and understood the information letter and signed the non-opposition form
- Patient follow-up at the Charles Nicolle University Hospital in Rouen
You may not qualify if…
- Other active cancer or hematological malignancy
- Contra-indication to surgery
- Patient not affiliated to the social security system
- Pregnant woman or parturient or breastfeeding
- Person under court protection, sub guardianship or curatorship
Where it is running
- Chu Rouen — Rouen, France (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.