EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke

Status unconfirmed · Not applicable

Conditions studied: Stroke, Hemiparesis

In brief

The goal of this study is to develop a clinically feasible, low-cost, nonsurgical neurorobotic system for restoring function to motor-impaired stroke survivors that can be used at the clinic or at home. Moreover, another goal is to understand how physical rehabilitation assisted by robotic device combined with electroencephalograph (EEG) can benefit adults who have had stroke to improve functions of their weaker arm. The proposed smart co-robot training system (NeuroExo) is based on a physical upper-limb robotic exoskeleton commanded by a non-invasive brain machine interface (BMI) based on scalp EEG to actively include the participant in the control loop . The study will demonstrate that the Neuroexo smart co-robot arm training system is feasible and effective in improving arm motor functions in the stroke population for their use at home.The NeuroExo study holds the promise to be cost-effective patient-centered neurorehabilitation system for improving arm functions after stroke.

Key facts

Study ID

NCT05374486

Run by

University of Houston

People needed

30

Starts

2022-04-25

Expected to finish

2022-08-01

Last updated by the study team

2022-05-16

Who can join

Age: 20 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• subjects between the ages of 20-65, male or female,
• mild-to- moderate unilateral stroke confirmed by brain CT or MRI scan and manifested by a Glasgow Coma scale (GCS) score between 15 and 9 documented within 6 months,
• the ability to perform 20deg of active wrist/elbow for upper limb robotic movement on the affected side, no planned alteration in lower/upper- extremity therapy/medication for muscle tone during course of study,
• Anticipated length of needed acute interdisciplinary rehabilitation of 30 days or more.
• Patients are required to have a MMSE>=24 to rule out those with cognitive impairments.
• Patients will have to have normal/near normal strength in one upper/lower extremity and appreciable weakness in the other upper/lower extremity.

You may not qualify if…

• history of traumatic brain injury prior to the current episode,
• Severe neurologic or psychiatric condition preventing participation in rehabilitation and physical therapy activities (patients unable or unwilling to receive instruction and effectively complete a simple assigned task as determined by MMSE>=24 specified in inclusion criteria).
• Women and minorities will be recruited as long as they meet the inclusion criteria.

Where it is running

• TIRR Memorial Hermann Hospital — Houston, Texas, United States (enrolling)
• University of Houston — Houston, Texas, United States (enrolling)
• The Institute for Rehabilitation and Research (TIRR) at Memorial Hermann — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.