Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

Completed · Not applicable

Conditions studied: Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary, Mediastinal Diseases

In brief

The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.

Key facts

Study ID

NCT05374447

Run by

George Washington University

People needed

55

Starts

2022-06-10

Expected to finish

2026-02-11

Last updated by the study team

2026-04-14

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Radiologic evidence of mediastinal and/or hilar lymphadenopathy
• Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
• Age 18 years or older
• Exclusion Criteria*:
• These are the characteristics that a participant must NOT have in order to be eligible to participate in the study.
• Order Number Criteria
• Severe pulmonary hypertension
• Inability to undergo general anesthesia
• Severe coagulopathy or bleeding diathesis
• Previously diagnosed sarcoidosis
• Patient presently taking clopidogrel
• Patient deemed to be high risk for general anesthesia per anesthesiologist
• Hemodynamic instability
• Mediastinitis
• Acute Hypercarbic Respiratory Failure (pCO2 >55mmHg)

Where it is running

• The George Washington University Hospital — Washington D.C., District of Columbia, United States

Full record on ClinicalTrials.gov

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