Nanopore Sequencing in Ophthalmology

Recruiting now

Conditions studied: Endophthalmitis

In brief

In this pilot study, the feasibility of the Oxford Nanopore MinION to identify pathogens from vitrectomy samples in eyes with endophthalmitis shall be assessed. The MinION is a low cost commercially available device for DNA/ RNA analysis that, in studies, has been used for pathogen determination in various infectious diseases as well as for the genetic characterization of hematologic tumors.

Key facts

Study ID

NCT05372861

Run by

Medical University of Graz

People needed

20

Starts

2022-04-22

Expected to finish

2027-12-01

Last updated by the study team

2025-09-30

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eyes of patients with endophthalmitis

You may not qualify if…

• No informed consent possible
• Participation in other studies

Where it is running

• Universitäts Augenklinik Graz — Graz, Styria, Austria (enrolling)

Full record on ClinicalTrials.gov

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