Quercetin's Effect on Bone Health and Inflammatory Markers

Completed · Not applicable · Has a placebo group

Conditions studied: Osteoporosis, Postmenopausal

In brief

Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables, and is considered to be a potent antioxidant with several expected health benefits such as anti-inflammatory effects and bone-conserving properties. Participants will supplement with either Quercetin, or placebo, for 90-days with pre- and post-testing visits.

Key facts

Study ID

NCT05371340

Run by

Kennesaw State University

People needed

33

Starts

2019-08-27

Expected to finish

2020-04-27

Last updated by the study team

2022-05-12

Who can join

Age: 45 and older, up to 75. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Clinically defined as postmenopausal (absence of menstrual cycle for 12 months without contraceptives or the surgical removal of the reproductive organs)
• Activity levels ranging from sedentary to recreationally active were included in the study.

You may not qualify if…

• Hyper- or hypothyroidism (uncontrolled)
• Hyper- or hypoparathyroidism
• Gastrointestinal disorders
• Renal disorders
• Orthopedic disorders
• Rheumatological disorders
• Immunological disorders
• Type I diabetic
• Being treated with any diabetic injectable medication(s).
• Taking any non-steroidal, steroidal, or anti-inflammatory drugs
• Currently, or in the past 1 month, were consuming daily calcium
• Currently, or in the past 1 month, were consuming more than 5,000 IU's of vitamin D supplements
• Taking any anti-obesity medications
• Taking any osteoporotic medication(s)
• Taking any long-term antibiotics.
• Current smoker
• Diagnosed with osteoporosis, or if their BMD was equal to, or fell below -2.50 via dual x-ray absorptiometry (DXA) during visit 1
• Involved in heavy resistance training
• Began a new unaccustomed exercise routine during the 90-days
• Allergies to food(s) rich in QUE such as onions, apples, or berries; or if they were unwilling to avoid quercetin-containing foods.

Where it is running

• Kennesaw State University — Kennesaw, Georgia, United States

Full record on ClinicalTrials.gov

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