Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)

Recruiting now · Not applicable

Conditions studied: PPAP, Spine Fusion

In brief

The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.

Key facts

Study ID

NCT05367609

Run by

Senthil Sadhasivam

People needed

300

Starts

2022-09-20

Expected to finish

2027-10-30

Last updated by the study team

2026-04-13

Who can join

Age: 10 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children ages 10 to 21
• ASA physical status 1 to 3
• Undergoing Posterior-Lateral Spinal Fusion
• Receives in-patient opioids
• Prescribed opioids at discharge

You may not qualify if…

• Serious illness
• Preoperative severe pain
• Preoperative opioid use or misuse

Where it is running

• University of California — San Francisco, California, United States (enrolling)
• Riley Children's Hospital — Indianapolis, Indiana, United States (enrolling)
• UPMC Children's Hospital — Pittsburgh, Pennsylvania, United States (enrolling)
• Children's Orthopaedic and Scoliosis Surgery Associates, LLP — St. Petersburg, Florida, United States
• Johns Hopkins All Children's Hospital — St. Petersburg, Florida, United States

Full record on ClinicalTrials.gov

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