Olfactory Training on Smell Dysfunction Patients in HK

Recruiting now · Not applicable

Conditions studied: Olfaction Disorders, Smell Disorders, Anosmia, Hyposmia, Olfactory Impairment, Smell Loss, Smell Dysfunction

In brief

* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.

Key facts

Study ID

NCT05364125

Run by

Pamela Youde Nethersole Eastern Hospital

People needed

80

Starts

2022-07-01

Expected to finish

2027-06-30

Last updated by the study team

2025-06-03

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Olfactory dysfunction > 6 months and < 5 years

You may not qualify if…

• History of significant head injury (fracture, ICH)
• History of brain surgery
• History of nasal surgery
• Active nasal disease
• Active neurological disease
• Poor premorbid status/ non-communicable patients
• Mentally incompetent patients
• <18 years' old
• Pregnancy
• Hypersensitivity to the aromatic substance.

Where it is running

• Pamela Youde Nethersole Eastern Hospital — Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.