Effect of Multiple Perforations of the Sinus Floor on Bone Formation After Sinus Floor Elevation

Recruiting now · Not applicable

Conditions studied: Sinus Elevation, Dental Implant, Bone Formation

In brief

The aim of the present study is to compare the rate of new bone formation after sinus floor elevation with or without perforation of the cortical sinus floor prior to insertion of augmentation material. Twelve patients requiring bilateral sinus floor elevation will be recruited for a pilot study in split-mouth design. On both sides a lateral window will be prepared and the sinus mucosa will be elevated. After this step, the sides are assigned as test or control side. While the control side is just filled with augmentation material, an additional step is performed for the test side, i.e., prior to inserting the augmentation material, the cortical bone layer of the sinus floor is perforated several times into the trabecular bone layer to improve the blood supply to the grafting material. Thereafter, both sides are left to healing for 4-6 months until implant installation. At timepoint of implant installation, a bone biopsy will be collected to allow histological assessment of the grafted area.

Key facts

Study ID

NCT05362136

Run by

Medical University of Vienna

People needed

12

Starts

2017-03-23

Expected to finish

2027-12-01

Last updated by the study team

2022-05-11

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• in need of bilateral sinus floor elevation
• residual alveolar ridge height 2-6mm
• residual alveolar ridge width > 4mm

You may not qualify if…

• uncontrolled periodontal disease
• acute or chronic sinusitis

Where it is running

• University Clinic of Dentistry, Medical University of Vienna — Vienna, Austria (enrolling)

Full record on ClinicalTrials.gov

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