Recording of Intraoperative Spinal Cord Stimulation and Monitoring

Recruiting now · Not applicable

Conditions studied: Cervical Stenosis, Disk, Herniated, Spondylosis

In brief

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Key facts

Study ID

NCT05356286

Run by

University of California, Los Angeles

People needed

150

Starts

2011-01-21

Expected to finish

2027-01-22

Last updated by the study team

2025-03-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

You may not qualify if…

• none

Where it is running

• University of California, Los Angeles — Los Angeles, California, United States (enrolling)

Full record on ClinicalTrials.gov

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