Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

Completed · Phase 3

Conditions studied: Respiratory Failure, Hypotension and Shock, Hypotension on Induction, Intubation Complication, Anesthesia Intubation Complication

In brief

The purpose of this study is to investigate whether protocolized vasopressor use for patients with normal blood pressure undergoing rapid sequence intubation improves hemodynamic parameters and mitigates adverse events. The hypothesis is that use of vasopressors during Rapid Sequence Intubation will prevent substantial decreases in blood pressure when compared to normal intravenous fluids.

Key facts

Study ID

NCT05355974

Run by

Wright State University

People needed

42

Starts

2022-08-09

Expected to finish

2024-07-10

Last updated by the study team

2024-07-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Respiratory Failure Requiring Intubation

You may not qualify if…

• Pregnancy
• Patients intubated during code blue clinical scenarios
• Requiring surgical airway
• Failed intubations
• MAP less than 65 or Systolic Blood Pressure (SBP) less than 90mmHg pre-intubation
• Systolic blood pressure greater than 150mmHg
• Prisoners

Where it is running

• Miami Valley Hospital Premier Health — Dayton, Ohio, United States

Full record on ClinicalTrials.gov

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