Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity

In brief

The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the investigators are investigating whether there is a dose-dependent response to tDCS.

Key facts

Study ID

NCT05354232

Run by

Massachusetts General Hospital

People needed

60

Starts

2022-07-01

Expected to finish

2026-05-01

Last updated by the study team

2025-12-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female outpatients 18-65 years of age
• A diagnosis of ADD/ADHD or meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.

You may not qualify if…

• Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, VP shunt, pacemakers, pregnancy.
• Active substance dependence (except for tobacco).
• Pregnant or nursing females.
• Inability to participate in testing procedures.
• Premorbid neurological conditions (including neurovascular and neurodegenerative diseases such as traumatic brain injury, stroke, Parkinson's, AD and other dementias) and severe psychiatric disorders (bipolar disorder, schizophrenia).

Where it is running

• Massachusetts General Hospital — Charlestown, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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