PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men

Completed · Not applicable

Conditions studied: Risk Reduction

In brief

Despite advances in HIV prevention, the HIV incidence among young men who have sex with men (YMSM) is increasing, threatening to derail achievement of the United States End the HIV Epidemic goals. Although, pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention method, adherence was sufficiently low to comprise efficacy among a high proportion of YMSM in multiple clinical trials and demonstration projects. In this study, the investigators will leverage a novel urine point-of-care drug-level test for PrEP adherence, to both enhance and target motivational-interviewing-based adherence counseling among YMSM, with the goal of preventing HIV infections among this critically at-risk group.

Key facts

Study ID

NCT05353283

Run by

University of California, San Francisco

People needed

63

Starts

2023-09-01

Expected to finish

2025-07-01

Last updated by the study team

2026-02-13

Who can join

Age: 18 and older, up to 30. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Male sex at birth who has sex with men
• Age 18-30 years-old
• Currently receiving tenofovir-based oral PrEP
• Plans to continue taking daily PrEP over the upcoming 3 months

You may not qualify if…

• Participant living with HIV
• Age > 30 years

Where it is running

• University of California, San Francisco/San Francisco General Hospital — San Francisco, California, United States

Full record on ClinicalTrials.gov

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