Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex

Running, not enrolling · Not applicable

Conditions studied: Cerebellar Ataxia

In brief

This study will determine (1) whether baseline inhibitory activity in the primary motor cortex can predict motor learning ability in individuals with cerebellar degeneration, and (2) whether modulating primary motor cortex activity with non-invasive brain stimulation alters motor learning ability in this population.

Key facts

Study ID

NCT05351255

Run by

Albert Einstein Healthcare Network

People needed

17

Starts

2022-07-01

Expected to finish

2026-12-19

Last updated by the study team

2025-09-15

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of cerebellar ataxia from cerebellar degeneration
• Normal or corrected-to-normal vision
• Normal or corrected-to-normal hearing
• Meet safety criteria for receipt of transcranial magnetic stimulation

You may not qualify if…

• Extrapyramidal signs on neurologic examination
• History of alcohol or illicit drug abuse
• Peripheral sensory loss in the arms
• Cognitive or attention deficits that interfere with testing, the capacity to understand and follow task instructions, or the capacity to provide informed consent
• Orthopedic injury or pain in the arms

Where it is running

• Moss Rehabilitation Research Institute — Elkins Park, Pennsylvania, United States

Full record on ClinicalTrials.gov

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