Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS
Stopped early · Phase 2 · Has a placebo group
Conditions studied: Amyotrophic Lateral Sclerosis
In brief
This study will assess the efficacy and safety of PTC857 treatment in participants diagnosed with ALS.
Key facts
- Study ID
- NCT05349721
- Run by
- PTC Therapeutics
- People needed
- 336
- Starts
- 2022-05-15
- Expected to finish
- 2025-01-30
- Last updated by the study team
- 2025-08-01
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Forbes Norris MDA/ALS Research Center at California Pacific Medical Center — San Francisco, California, United States
- Holy Cross Hospital, Phil Smith Neuroscience Institute — Fort Lauderdale, Florida, United States
- University of South Florida - Carol and Frank Morsani Center for Advanced Healthcare — Tampa, Florida, United States
- Augusta University — Augusta, Georgia, United States
- University of Kansas Medical Center (KUMC) - Landon Center on Aging — Kansas City, Kansas, United States
- Henry Ford Health System Department of Neurology — Detroit, Michigan, United States
- Neurology Associates, P.C. / Somnos Clinical Research — Lincoln, Nebraska, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- Providence Brain and Spine Institute — Portland, Oregon, United States
- Lewis Katz School of Medicine at Temple Universtiy — Philadelphia, Pennsylvania, United States
- National Neuromuscular Research Institute — Austin, Texas, United States
- Nerve and Muscle Center of Texas — Houston, Texas, United States
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
- STAT Research S.A. — Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
- Iadin Srl. — Buenos Aires, Argentina
- Hospital Ramos Mejía — Buenos Aires, Argentina
- Royal Brisbane and Women's Hospital — Brisbane, Queensland, Australia
- Gold Coast Hospital — Southport, Queensland, Australia
- Calvary Health Care Bethlehem — Caulfield South, Victoria, Australia
- Austin Health — Heidelberg, Victoria, Australia
- AZ Sint-Lucas Gent — Ghent, Belgium
- UZ Leuven — Leuven, Belgium
- University hospital Brno, Department of Neurology — Brno, Czechia
- FORBELI s.r.o. — Prague, Czechia
- UC Irvine Health ALS and Neuromuscular Center — Orange, California, United States
Full record on ClinicalTrials.gov
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