Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection

Running, not enrolling · Not applicable

Conditions studied: Cryotherapy Effect, Pain, Postoperative

In brief

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection. There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

Key facts

Study ID

NCT05348447

Run by

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

People needed

110

Starts

2022-04-21

Expected to finish

2026-03-20

Last updated by the study team

2026-02-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients 18 year and older.
• Undergoing elective minimally invasive (VATS or robotic) lung resection for nodules (wedge resection, segmentectomy, lobectomy).
• Performance status of 1 or 2.

You may not qualify if…

• Patients with ejection fraction less than 40%
• Patients with creatinine greater than 1.5.
• Patients with Child's B or C cirrhosis
• Patients on chronic narcotics for other reasons
• Patients diagnosed with fibromyalgia
• Patients who had previous thoracic surgery on the same side.
• Patients who cannot communicate in English.
• Patients unable to provide informed consent for the study.

Where it is running

• AHN Allegheny General Hospital — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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