Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency

Running, not enrolling · Phase 3 · Has a placebo group

Conditions studied: OTC Deficiency

In brief

The primary objective is to evaluate the efficacy of DTX301 on the improvement of ornithine transcarbamylase (OTC) function by maintaining safe plasma ammonia levels.

Key facts

Study ID
NCT05345171
Run by
Ultragenyx Pharmaceutical Inc
People needed
37
Starts
2022-10-18
Expected to finish
2031-03-01
Last updated by the study team
2026-06-02

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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