Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Schizophrenia, Schizo Affective Disorder

In brief

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study the investigators will be stimulating the brain to learn more about how TMS might improve these symptoms of schizophrenia.

Key facts

Study ID

NCT05343598

Run by

Mclean Hospital

People needed

68

Starts

2021-10-13

Expected to finish

2026-10-31

Last updated by the study team

2026-01-22

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of schizophrenia or schizoaffective disorder

You may not qualify if…

• substance use disorder in past 3 months
• ambidexterity
• contraindications for TMS or MRI including :
• history of neurological disorder
• history of head trauma resulting in loss of consciousness
• history of seizures or diagnosis of epilepsy or first degree relative family history of epilepsy
• metal in brain or skull
• implanted devices such as a pacemaker, medication pump, nerve stimulator or ventriculoperitoneal shunt
• claustrophobic in MRI

Where it is running

• McLean Hospital — Belmont, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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