Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension

Recruiting now

Conditions studied: Chronic Thromboembolic Pulmonary Hypertension

In brief

Chronic ThromboEmbolic Pulmonary Hypertension (CTEPH) is a rare but severe complication of pulmonary embolism (PE). CTEPH is evoked in patients with persistent dyspnea. According to international guidelines, symptomatic patients with perfusion defects on lung scan and Pulmonary Hypertension (PH)-likely transthoracic echo (TTE) must be evaluated in Pulmonary Hypertension (PH)-centers with right heart catheterism, to confirm or rule out the presence of precapillary Pulmonary Hypertension (PH), and precise the group of Pulmonary Hypertension (PH).

Key facts

Study ID

NCT05340023

Run by

Centre Hospitalier Universitaire de Saint Etienne

People needed

120

Starts

2022-11-09

Expected to finish

2027-05-01

Last updated by the study team

2025-11-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient with a suspicion of Chronic thromboembolic pulmonary hypertension (CTEPH) with a combination of a perfusion lung scan and transthoracic perfusion scan and transthoracic echocardiography compatible with the diagnosis (according to French recommendations)
• Patients who require a right heart catheterization.
• Patient affiliated or entitled to a social security plan
• Patient having received informed information about the study informed about the study

You may not qualify if…

• Patient with a normal perfusion lung scan
• Person under legal guardianship

Where it is running

• CHU de SAINT-ETIENNE — Saint-Etienne, France (enrolling)

Full record on ClinicalTrials.gov

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