Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment

Completed · Phase 4

Conditions studied: Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis

In brief

This study will assess the efficacy of two local anesthetics (2% lidocaine 1:100,000 epinephrine and 0.5% bupivicaine 1:200,000 epinephrine) in reducing post-operative pain in patients receiving endodontic treatment.

Key facts

Study ID

NCT05338671

Run by

University of Washington

People needed

35

Starts

2021-09-29

Expected to finish

2024-06-01

Last updated by the study team

2025-05-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnosis of symptomatic irreversible pulpitis on mandibular, posterior tooth
• ASA I or II
• >18 years old

You may not qualify if…

• Maxillary or mandibular anterior tooth
• Diagnosis of pulp necrosis or reversible pulpitis
• Tooth deemed non-restorable
• <18 years old
• ASA III, IV, or V
• Patients who are contraindicated to take ibuprofen
• Patients with allergies to any medications being assessed in this study

Where it is running

• University of Washington- School of Dentistry — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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