China HeadAche DIsorders RegiStry

Recruiting now

Conditions studied: Headache Disorders, Primary, Migraine, New Daily Persistent Headache, Medication Overuse Headache, Tension-Type Headache, Trigeminal Autonomic Cephalalgia

In brief

It is planned to include 10000 patients. In the China HeadAche DIsorders RegiStry CHAIRS）, patients aged over 12 years with primary headache and medication-overuse headache(MOH) were collected. The biomarkers, imaging features, cognition, genetic characteristics, ocial and demographic data, medical data, therapeutics used, and outcome of headache-related diseases were studied, and long-term follow-up was planned.

Key facts

Study ID

NCT05334927

Run by

Beijing Tiantan Hospital

People needed

10000

Starts

2022-08-29

Expected to finish

2032-12-31

Last updated by the study team

2026-07-10

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 12 years old,Any gender;
• The first onset age of primary headache was less than 50 years old(Age <65 years at first diagnosis of chronic migraine);
• patients with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3;
• Sign the informed consent form.

You may not qualify if…

• According to the ICHD-3 diagnostic criteria, there are still headaches directly related to secondary factors (except drug overuse) at the time of enrollment;
• Those who cannot be diagnosed as primary headache or primary headache combined with medication overuse headache according to ICHD-3;
• According to DSM-V diagnostic criteria, patients with severe mental diseases (such as schizophrenia, mental disorders associated with mental retardation, etc.);
• Patients with severe organic diseases, such as malignant tumors, and the expected survival time is less than 1 year;
• Pregnant,planning pregnancy or Lactating women;
• Subjects participating in other clinical trials;
• Unable to cooperate to complete the follow-up due to geographical or other reasons

Where it is running

• The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital) — Wuhu, Anhui, China (enrolling)
• Beijing Tiantan Hospital, Capital Medical University — Beijing, Beijing Municipality, China (enrolling)
• Beijing Chaoyang Hospital — Beijing, Beijing Municipality, China (enrolling)
• Peking University Third Hospital — Beijing, Beijing Municipality, China (enrolling)
• The First Hospital of Fangshan District, Beijing — Beijing, Beijing Municipality, China (enrolling)
• Chongqing People's Hospital — Chongqing, Chongqing Municipality, China (enrolling)
• The Third Affiliated Hospital of Chongqing Medical University — Chongqing, Chongqing Municipality, China (enrolling)
• Fujian Provincial Hospital — Fuzhou, Fujian, China (enrolling)
• The First Affiliated Hospital of Xiamen University — Xiamen, Fujian, China (enrolling)
• The Second Affiliated Hospital of Xiamen Medical College — Xiamen, Fujian, China (enrolling)
• The Second Hospital of Lanzhou University — Lanzhou, Gansu, China (enrolling)
• Shenzhen Second People's Hospital — Shenzhen, Guangdong, China (enrolling)
• The First Affiliated Hospital of Guangxi University of Chinese Medicine — Nanning, Guangxi, China (enrolling)
• The Second Affiliated Hospital of Guangxi Medical University — Nanning, Guangxi, China (enrolling)
• The Second People's Hospital of Guiyang — Guiyang, Guizhou, China (enrolling)
• The First People's Hospital of Zunyi — Zunyi, Guizhou, China (enrolling)
• Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine — Qionghai, Hainan, China (enrolling)
• Qinhuangdao Haigang Hospital — Qinhuangdao, Hebei, China (enrolling)
• Zhongnan Hospital of Wuhan University — Wuhan, Hebei, China (enrolling)
• Qinghe County People's Hospital — Xingtai, Hebei, China (enrolling)
• The First Affiliated Hospital of Hebei North University — Zhangjiakou, Hebei, China (enrolling)
• Yangyuan County People's Hospital — Zhangjiakou, Hebei, China (enrolling)
• Zhangjiakou First Hospital — Zhangjiakou, Hebei, China (enrolling)
• The Second Affiliated Hospital of Harbin Medical University — Harbin, Heilongjiang, China (enrolling)
• Anqing Municipal Hospital — Anqing, Anhui, China (enrolling)

Full record on ClinicalTrials.gov

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