The Effect of Beta-blocker on Chronotropic Response and Cardiorespiratory Fitness in Patients With Atrial Fibrillation
Recruiting now · Not applicable
Conditions studied: Atrial Fibrillation
In brief
This is a prospective study to evaluate changes in exercise capacity and chronotropic response to exercise before and after beta-blocker dosage reduction in patients with atrial fibrillation (AF).
Key facts
- Study ID
- NCT05332457
- Run by
- National Taiwan University Hospital
- People needed
- 40
- Starts
- 2025-07-01
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2025-03-24
Who can join
Age: 20 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- > 20 years of age.
- Clinically stable patients with persistent atrial fibrillation using beta-blocker as rate-control agent without dosage adjustment for at least 3 months.
- Resting heart rate < 80 bpm.
- Left ventricular ejection fraction > 50%.
You may not qualify if…
- Beta-blocker usage due to indications other than rate control for atrial fibrillation.
- Inability to perform a cardiopulmonary exercise testing.
- Presence of contraindications for cardiopulmonary exercise testing according to the American College of Sports Medicine's Guidelines for Exercise Testing and Prescription.
- Patients with implantable cardioverter defibrillator or pacemaker.
- Pregnancy.
- Inability to provide informed consent.
Where it is running
- National Taiwan University Hospital — Taipei, Taiwan (enrolling)
Full record on ClinicalTrials.gov
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