Surgery or Chemoradiotherapy for Cervical Esophageal Cancer
Recruiting now · Not applicable
Conditions studied: Cervical Esophageal Cancer
In brief
To compare surgery with definitive chemoradiotherapy for patients with resectable cervical esophageal squamous cell carcinoma.
Key facts
- Study ID
- NCT05327517
- Run by
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- People needed
- 192
- Starts
- 2022-04-10
- Expected to finish
- 2028-12-31
- Last updated by the study team
- 2022-04-14
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients with resectable cervical esophageal squamous cell carcinoma (cT1b-T4aN0-3M0);
- Cervical esophageal cancers spreads upwards to involve the hypopharynx and downwards to involve the thoracic esophagus can also be included;
- Aged 18-75 years;
- Without any contraindication of operation;
- Hemoglobin >=90 g/L; Leukocytes >=4.0x10\^9/L; Absolute neutrophil count >=1.5x10\^9/L; Platelet >=100x10\^9/L;Total bilirubin <=1.5 ULN; ALT <=2.5 ULN; AST <=2.5 ULN; Serum creatinine <=1.5 ULN or creatinine clearance rate >=50 mL/min (Cocheroft-Gault);INR <=1.5 ULN; APTT <=1.5 ULN;
- Without other malignancies;
- Expected R0 resection;
- ECOG PS 0-1;
- Volunteered to participate in the study, signed the informed consent form.
You may not qualify if…
- Without other malignancies;
- With mental diseases;
- With hemorrhagic disease;
- Inoperable patients;
- Pregnant or lactating women;
- Has a history of allergy to paclitaxel or cisplatin
Where it is running
- Cancer Hospital Chinese Academy of Medical Sciences — Beijing, China (enrolling)
Full record on ClinicalTrials.gov
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