The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients

Recruiting now · Not applicable

Conditions studied: Cirrhosis, Liver, Splenectomy; Status

In brief

In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.

Key facts

Study ID

NCT05325424

Run by

Northern Jiangsu People's Hospital

People needed

20

Starts

2022-03-01

Expected to finish

2025-07-31

Last updated by the study team

2025-05-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
• Splenomegaly with secondary hypersplenism, Platelet count < 50*10\^9/L
• Informed consent to participate in the study

You may not qualify if…

• Hepatocellular carcinoma or any other malignancy,
• Child-Pugh grade C
• Recent peptic ulcer disease
• History of Hemorrhagic stroke
• Pregnancy.
• Uncontrolled Hypertension
• Bleeding portal hypertension
• Human immunodeficiency virus (HIV) infection

Where it is running

• Clinical Medical College of Yangzhou University — Yangzhou, Jiangsu, China (enrolling)

Full record on ClinicalTrials.gov

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