Elbow Artery Embolization for Tennis Elbow

Running, not enrolling · Not applicable

Conditions studied: Lateral Epicondylitis, Unspecified Elbow

In brief

The purpose of this clinical research study is to examine whether embolization treatment of an elbow artery is a safe and effective way to treat elbow pain, specifically pain from tennis elbow. Embozene is a medical device made by Varian marketed in the United States for the treatment of hypervascular tumors and arteriovenous malformations. It consists of thousands of microscopic spheres that are injected into the artery to block the flow of blood to a specific region. One of the causes of pain in the setting of tennis elbow is increased blood flow going to the specific area of pain. In this study, we will investigate an experimental procedure to decrease the blood flow (embolize) to the specific region of the elbow that is causing the pain. This will be done by infusing Embozene particles into the specific blood vessel supplying the area of pain in the elbow. This is an investigational study to evaluate the safety and efficacy of elbow artery embolization (EAE) for the treatment of symptomatic lateral epicondylitis (tennis elbow).

Key facts

Study ID

NCT05325242

Run by

Siddharth Padia, MD

People needed

13

Starts

2023-03-21

Expected to finish

2027-12-31

Last updated by the study team

2026-06-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Diagnosis of lateral epicondylitis based on history and physical exam
• Ability to provide informed consent
• Life expectancy greater than 12 months
• Moderate-severe lateral elbow pain as determined by visual analog scale > 4 (based on average severity during physical activity)
• Resistant/failed conservative treatment (e.g. NSAIDS/physical therapy/steroid joint injection) for at least 6 months.

You may not qualify if…

• Mild elbow pain as determined by visual analog scale < 4
• Chronic renal insufficiency (serum creatinine >2 mg/dL)
• Allergy to iodinated contrast agents that is not responsive to steroid management
• Active Infection or malignancy
• Prior elbow surgery in the subject elbow
• Uncorrectable bleeding diathesis

Where it is running

• University of California, Los Angeles — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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