Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Recruiting now · Not applicable

Conditions studied: Urothelial Carcinoma

In brief

To evaluate the ability of \[68Ga\]N188 to detect nectin-4 overexpression in patients with urothelial carcinoma, especially in patients with recurrent or advanced bladder cancer.

Key facts

Study ID

NCT05321316

Run by

Peking University Cancer Hospital & Institute

People needed

20

Starts

2026-05-31

Expected to finish

2026-12-01

Last updated by the study team

2026-03-04

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-75 years old, male or female;
• Heart function is normal;
• Normal heart function;
• Estimated survival ≥12 weeks;
• Good follow-up compliance;
• presence of at least one measurable target lesion according to RECIST1.1 criteria;
• Women of childbearing age (15-49 years) must have a negative pregnancy test within 7 days before starting the test; Fertile men and women must agree to use effective contraception to prevent pregnancy during the study period and for 3 months after the test;
• Patients recommended by clinicians to undergo PET/CT examination for tumor diagnostic staging;
• The subject patients could fully understand and voluntarily participate in the experiment, and signed the informed consent.

You may not qualify if…

• Serious abnormality of liver, kidney and blood;
• Pregnant patients;
• Pregnant and lactation women;
• unable to lie flat for half an hour; 4) Refuse to join the clinical investigator; 5) Suffering from claustrophobia or other mental diseases; 6) Other conditions that researchers deem unsuitable for participating in the experiment.

Where it is running

• Beijing Cancer Hospital — Beijing, Beijing Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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