A Study to Assess the Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of ION904 in Participants With Uncontrolled Hypertension

Completed · Phase 2 · Has a placebo group

Conditions studied: Hypertension

In brief

The purpose of this study is to evaluate the effect of ION904 on plasma angiotensinogen (AGT) in participants with uncontrolled hypertension.

Key facts

Study ID

NCT05314439

Run by

Ionis Pharmaceuticals, Inc.

People needed

48

Starts

2022-04-29

Expected to finish

2023-02-15

Last updated by the study team

2023-12-22

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Altasciences - Los Angeles — Cypress, California, United States
• National Research Institute — Los Angeles, California, United States
• Clinical Trials Research — Sacramento, California, United States
• ALL Medical Research, LLC — Cooper City, Florida, United States
• Progressive Medical Research — Port Orange, Florida, United States
• Altasciences — Overland Park, Kansas, United States
• NY Scientific — Brooklyn, New York, United States
• Juno Research, LLC — Houston, Texas, United States

Full record on ClinicalTrials.gov

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