Neurologic Physiology After Removal of Therapy (NeuPaRT)
Recruiting now
Conditions studied: Determination of Death
In brief
The purpose of this study is to determine when brain function stops compared to when the heart stops by monitoring electrical brain activity in patients who are taken off life support and progress to death in the intensive care unit.
Key facts
- Study ID
- NCT05306327
- Run by
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- People needed
- 158
- Starts
- 2022-10-18
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-01-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Plan for the withdrawal of life sustaining measures (WLSM)
- Attending physician anticipates patient will die within 24 hours of the withdrawal of life sustaining measures
- Patient has an indwelling arterial cannula for monitoring blood pressure
You may not qualify if…
- Brain death or plan for Neurologic Determination of Death (NDD)
- Injuries that anatomically preclude the use of neurologic monitoring
Where it is running
- University of Calgary Foothills Campus — Calgary, Alberta, Canada (enrolling)
- Kingston Health Sciences Centre — Kingston, Ontario, Canada (enrolling)
- London Health Sciences Centre — London, Ontario, Canada (enrolling)
- Ottawa Hospital — Ottawa, Ontario, Canada (enrolling)
- Centre hospitalier de l'Université de Montréal, — Montreal, Quebec, Canada (enrolling)
Full record on ClinicalTrials.gov
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