Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant
Stopped early · Phase 2/Phase 3 · Has a placebo group
Conditions studied: Adenovirus Infection, BK Virus Infection, Cytomegalovirus Infections, Epstein-Barr Virus Infections, Human Herpes Virus-6 Infection, JC Virus Infection
In brief
This is a Phase 3 study to evaluate posoleucel (ALVR105, Viralym-M); an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets six viral pathogens: BK virus, cytomegalovirus, adenovirus, Epstein-Barr virus, human herpesvirus 6 and JC virus.
Key facts
- Study ID
- NCT05305040
- Run by
- AlloVir
- People needed
- 451
- Starts
- 2022-03-24
- Expected to finish
- 2024-01-30
- Last updated by the study team
- 2024-05-16
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Honor Health Research Institute — Scottsdale, Arizona, United States
- City of Hope — Duarte, California, United States
- University of California, Los Angeles (UCLA) — Los Angeles, California, United States
- Stanford University — Palo Alto, California, United States
- University of California San Francisco - Benioff Children's Hospital — San Francisco, California, United States
- University of Colorado Hospital — Aurora, Colorado, United States
- Yale University School of Medicine - Yale Cancer Center — New Haven, Connecticut, United States
- Childrens National Health System — Washington D.C., District of Columbia, United States
- University of Florida (UF) - Gainesville — Gainesville, Florida, United States
- Moffitt Cancer Center — Tampa, Florida, United States
- Northside Hospital — Atlanta, Georgia, United States
- Loyola University Medical Center — Maywood, Illinois, United States
- Indiana University Hospital Simon Comprehensive Cancer Center — Indianapolis, Indiana, United States
- University of Kansas Hospital — Kansas City, Kansas, United States
- University of Maryland — Baltimore, Maryland, United States
- Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- Children's Mercy Hospital — Kansas City, Missouri, United States
- Washington University School of Medicine — St Louis, Missouri, United States
- Hackensack University Medical Center — Hackensack, New Jersey, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Columbia University — New York, New York, United States
- Weill Cornell Medical College — New York, New York, United States
- Stony Brook University Hospital Cancer Center — Stony Brook, New York, United States
- University of Alabama at Birmingham Children's of Alabama — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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