Investigating Myocardial Remodelling in the Failing Human Heart

Recruiting now

Conditions studied: Heart Failure

In brief

Despite improvements in therapy, heart failure is a disease with high mortality and accelerating prevalence. To improve patient care, it is necessary to better understand the features and underlying mechanisms of myocardial remodeling; how it manifests in vivo and its underlying cellular and extracellular changes. The RELAX study will offer insight into myocardial remodeling, by comprehensively assessing function and structure of failing human hearts, and investigate its underlying cellular and extracellular changes.

Key facts

Study ID

NCT05303896

Run by

Oslo University Hospital

People needed

200

Starts

2022-05-30

Expected to finish

2030-07-01

Last updated by the study team

2025-07-31

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Eligible for heart transplantation
• Willingness to participate in the present study and ability to understand and sign the written informed consent

You may not qualify if…

• Patients under the age of 18.

Where it is running

• Oslo University Hospital — Oslo, Oslo, Norway (enrolling)

Full record on ClinicalTrials.gov

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