Do EEG and Neurocognitive Assessments Correlate With COVID Brainfog Symptoms?
Completed
Conditions studied: COVID-19
In brief
Since the neurologic symptoms of some COVID patients ('brain fog') resemble those of patients with concussion, the aim of this study is to identify EEG and cognitive function changes in COVID patients. We will use the FDA cleared BrainScope medical device in conjunction with standard neurocognitive tests to identify correlations with electrical biomarkers and to potentially identify new, unique patterns of altered brain electrical activity associated with COVID-19 infection. A baseline assessment will be performed shortly after hospital presentation and then a second evaluation will be performed 45-60 days post hospital discharge to reassess clinical status, brain electrical biomarkers and neurocognitive performance. The goal will be to develop an objective measurement of brain function/dysfunction associated with COVID-19 infection which might be employed in future studies of treatments for COVID-19 brain fog and to aid in tracking recovery.
Key facts
- Study ID
- NCT05303116
- Run by
- Texas Tech University Health Sciences Center, El Paso
- People needed
- 55
- Starts
- 2022-04-21
- Expected to finish
- 2024-02-20
- Last updated by the study team
- 2025-05-18
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Current COVID 19 infection
- Experiencing 'brain fog' symptoms (e.g.confusion, mental slowness, unable to concentrate)
- GCS of 14 or 15
- sufficient mental capacity to provide informed consent
- hemodynamically stable
- able to cooperate with EEG collection and neurometric testing
- admitted to a floor bed rather than ICU
You may not qualify if…
- Head or facial trauma
- Any abnormality that would prevent electrodes from being placed on the head
- Known central nervous system (CNS) disease i.e. MS, Parkinson's disease
- Know seizure disorder
- Known dementia
- Metabolic encephalopathy i.e. uremia, hepatic
- Alcohol intoxication to the point they cannot give consent
- Hypoxia that is not corrected to 92% by nasal cannula, or simple face mask
- Chronic alcohol or drug dependence
- Prior cerebrovascular accident (CVA)
- Prior brain surgery
- Known brain mass
- Receiving sedation medications at time of consent
- End stage renal disease (ESRD) on dialysis
- Acute psychosis
Where it is running
- University Medical Center of El Paso — El Paso, Texas, United States
Full record on ClinicalTrials.gov
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