Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training

Completed · Not applicable

Conditions studied: Exercise Training

In brief

The purpose of this study is to examine the effect of human skeletal muscle temperature during resistance exercise on myogenic and proteolytic signaling. Subjects will perform bilateral resistance exercise bouts at an intensity that should stimulate a muscle growth response in the Vastus Lateralis. During the resistance exercise, the subjects will receive a cold (10°C) intervention on the experimental limb, while receiving a neutral temperature intervention (22°C) on the control limb.

Key facts

Study ID: NCT05302791
Run by: University of Nebraska
People needed: 12
Starts: 2022-04-19
Expected to finish: 2022-10-01
Last updated by the study team: 2024-10-08

Who can join

Age: 19 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Any male or female who is 19-45 of age and is considered
low risk for physical activity based on the American College of Sports Medicine (ACSM) guidelines
recreationally active during the 6 weeks prior to participation by meeting the ACSM minimum activity guidelines

You may not qualify if…

Any person outside of the age range of 19-45
not considered 'low risk' on the ACSM Risk Stratification Form
not meeting the exercise requirements for the preceding 6 weeks will be excluded.
self-report of a history of joint or muscular injury that would prevent them from safely completing the required activities
self-report of taking prescription drugs or supplements that may interfere with this research
self-report allergy to Xylocaine
pregnant
breast feeding
self-report sensitivity to heat or cold

Where it is running

University of Nebraska at Omaha — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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