Intravenous Fluid Administration's Effect on Pediatric Lumbar Puncture

Completed · Not applicable

Conditions studied: Pediatric Lumbar Puncture

In brief

The purpose of this project is to determine if administration of normal saline intravenous fluids prior to a lumbar puncture improves first time success of lumbar puncture in infants less than 3 months of age. First time success of lumbar puncture defined as cerebrospinal fluid obtained on the first attempt with less than 1000 red blood cells per mm3 in the fluid specimen.

Key facts

Study ID

NCT05302765

Run by

University of Alabama at Birmingham

People needed

182

Starts

2022-11-22

Expected to finish

2025-05-31

Last updated by the study team

2025-08-03

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 0 and 3 months
• Patient at Children's of Alabama's Emergency Department
• Undergoing a lumbar puncture as part of their clinical work-up

You may not qualify if…

• Vertebral abnormalities
• Severe scoliosis
• Lumbar puncture to be performed by interventional radiology
• Received intravenous fluids prior to study enrollment
• Hypotension requiring fluid resuscitation
• Shock requiring fluid resuscitation
• Ultrasound assistance
• Lumbar puncture performed or attempted at another hospital within 24 hours

Where it is running

• Children's of Alabama — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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