Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

Completed · Not applicable · Has a placebo group

Conditions studied: Hiv, Tobacco Smoking

In brief

To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation. We hypothesize 4 sessions of TBS to the left DLPFC will significantly improve attentional bias and craving for smoking cues compared to neutral cues in a population of subjects who are smokers with HIV/AIDS compared to sham stimulation.

Key facts

Study ID

NCT05295953

Run by

Gopalkumar Rakesh

People needed

4

Starts

2022-04-01

Expected to finish

2024-07-31

Last updated by the study team

2025-10-22

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Positive pregnancy test for females, traumatic brain injury, history of seizure disorder, history of or current diagnosis of schizophrenia, intracranial metal shrapnel.
• Previous adverse effect with TMS.
• Sub-threshold consistency while performing behavioral tasks.
• Failure to show baseline attentional bias to smoking versus neutral cues.

Where it is running

• 245 Fountain Court — Lexington, Kentucky, United States
• University of Kentucky — Lexington, Kentucky, United States

Full record on ClinicalTrials.gov

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